E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Research (Original Article) 


Clinico-biochemical and Electrocardiographic Changes in Cattle Naturally Infected with Lumpy Skin Disease

Mahmoud A.Y. Helal, Marawan A. Marawan, Halla E.K. El Bahgy.

Abstract
Lumpy skin disease (LSD) is an economically important viral disease of cattle caused by Capripox virus. The disease is characterized clinically by fever, nodules on the skin, mucous membranes and internal organs, emaciation, enlarged lymph nodes, edema of the skin and deaths in some cases. The aim of this study is to investigate the clinico-biochemical picture of LSD infected cattle with special reference to the cardiac abnormalities. This study was carried out on LSD infected cattle showing typical clinical signs of the disease in Kaliobia governorate (𝑛 = 50; and aged between 2 to 5 years old). Clinical and electrocardiographic examination (ECG) were performed firstly, then skin nodules were aseptically collected from infected cattle for molecular detection of LSDV using PCR, on the other hand, serum samples were collected for biochemical analysis. The results of the current study revealed that, all examined tissue samples showed successful amplification of the viral attachment protein gene of LSDV with presence of positive bands at the target size (192 bp). Furthermore, troponin I (cTnI), urea, creatinine ALT, AST, ALP and potassium were significantly increased in LSD infected cattle compared to the control ones. In contrast, serum calcium, iron and sodium concentrations were significantly decreased. The ECG of LSD infected cattle showed abnormal P waves, shortening of P and T-waves amplitudes and decrease in RT interval compared to healthy cattle. The cardiac alterations in case of LSD infection could be related to the elevation of cTnI because of direct effect of the virus on the heart beside electrolyte imbalance, acidosis and hypocalcaemia.

Key words: cardiac, cattle, electrocardiography, Troponin I, lumpy skin


 
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How to Cite this Article
Pubmed Style

Helal MA, Marawan MA, Bahgy HEE. Clinico-biochemical and Electrocardiographic Changes in Cattle Naturally Infected with Lumpy Skin Disease. AJVS. 2019; 60(1): 41-48. doi:10.5455/ajvs.20434


Web Style

Helal MA, Marawan MA, Bahgy HEE. Clinico-biochemical and Electrocardiographic Changes in Cattle Naturally Infected with Lumpy Skin Disease. http://www.alexjvs.com/?mno=20434 [Access: July 22, 2019]. doi:10.5455/ajvs.20434


AMA (American Medical Association) Style

Helal MA, Marawan MA, Bahgy HEE. Clinico-biochemical and Electrocardiographic Changes in Cattle Naturally Infected with Lumpy Skin Disease. AJVS. 2019; 60(1): 41-48. doi:10.5455/ajvs.20434



Vancouver/ICMJE Style

Helal MA, Marawan MA, Bahgy HEE. Clinico-biochemical and Electrocardiographic Changes in Cattle Naturally Infected with Lumpy Skin Disease. AJVS. (2019), [cited July 22, 2019]; 60(1): 41-48. doi:10.5455/ajvs.20434



Harvard Style

Helal, M. A., Marawan, . M. A. & Bahgy, . H. E. E. (2019) Clinico-biochemical and Electrocardiographic Changes in Cattle Naturally Infected with Lumpy Skin Disease. AJVS, 60 (1), 41-48. doi:10.5455/ajvs.20434



Turabian Style

Helal, Mahmoud A.Y., Marawan A. Marawan, and Halla E.K. El Bahgy. 2019. Clinico-biochemical and Electrocardiographic Changes in Cattle Naturally Infected with Lumpy Skin Disease. Alexandria Journal of Veterinary Sciences, 60 (1), 41-48. doi:10.5455/ajvs.20434



Chicago Style

Helal, Mahmoud A.Y., Marawan A. Marawan, and Halla E.K. El Bahgy. "Clinico-biochemical and Electrocardiographic Changes in Cattle Naturally Infected with Lumpy Skin Disease." Alexandria Journal of Veterinary Sciences 60 (2019), 41-48. doi:10.5455/ajvs.20434



MLA (The Modern Language Association) Style

Helal, Mahmoud A.Y., Marawan A. Marawan, and Halla E.K. El Bahgy. "Clinico-biochemical and Electrocardiographic Changes in Cattle Naturally Infected with Lumpy Skin Disease." Alexandria Journal of Veterinary Sciences 60.1 (2019), 41-48. Print. doi:10.5455/ajvs.20434



APA (American Psychological Association) Style

Helal, M. A., Marawan, . M. A. & Bahgy, . H. E. E. (2019) Clinico-biochemical and Electrocardiographic Changes in Cattle Naturally Infected with Lumpy Skin Disease. Alexandria Journal of Veterinary Sciences, 60 (1), 41-48. doi:10.5455/ajvs.20434





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