E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Article 


Experimental Studies on Some Zoonotic Diarrheagenic Agents in Albino Rats

Mohamed A. Nossair, Mousa A. Ayoub, Reham S. El-Maadawy, Sabah I. Shaaban.

Abstract
Since various pathogens or factors have been implicated in the development of diarrheic disease, laboratory testing is necessary for accurate diagnosis. The current study was designed to obtain an idea about the pathological effect of Salmonella, E.coli and Cryptosporidium on GIT in rat model. A total of 48 early mature, male albino rats (Swiss Webster) were used to study the course of the infection with E.coli O18, S. Enteritidis and Cryptosporidium during a 30-day period, with special emphasis on clinical signs, bacterial dissemination, oocyst shedding and finally histopathologic changes in target organs. The results revealed that E. coli 018 had pathogenic potential in rats. Shedding of E. coli organisms in faeces detected from 2nd day post infection (PI) by conventional culture methods. While, using quantitative real time PCR (qPCR) it was detected for longer periods. In Salmonella infected group, shedding o f S. Enteritidis was detected only in 2nd day PI by conventional methods while by using qPCR was detected for longer periods. Cryptosporidium oocyst shedding in immunocompetent rats began on the day 4 PI and reached the peak on day 11 PI. The intensities of oocyst shedding were significantly greater in the immunosuppressed rats than in the non-immunosuppressed ones. The results of this study confirmed the use of rat model in the experimental infections to evaluate the negative impacts of diarrheic agents on human health is of great value and it is required to understand the pathogenesis of these infectious agents as these models help us to make simulation for human host. They also help to evaluate the diagnostic procedures that would help in development of control programs.

Key words: Salmonella, E. coli, Cryptosporidium, Experimental, Studies, Rats,


 
ARTICLE TOOLS
Abstract
PDF Fulltext
ePub Reader
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Mohamed A. Nossair
Articles by Mousa A. Ayoub
Articles by Reham S. El-Maadawy
Articles by Sabah I. Shaaban
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Nossair MA, Ayoub MA, El-Maadawy RS, Shaaban SI. Experimental Studies on Some Zoonotic Diarrheagenic Agents in Albino Rats. AJVS. 2018; 58(1): 196-207. doi:10.5455/ajvs.1176


Web Style

Nossair MA, Ayoub MA, El-Maadawy RS, Shaaban SI. Experimental Studies on Some Zoonotic Diarrheagenic Agents in Albino Rats. https://www.alexjvs.com/?mno=1176 [Access: December 04, 2023]. doi:10.5455/ajvs.1176


AMA (American Medical Association) Style

Nossair MA, Ayoub MA, El-Maadawy RS, Shaaban SI. Experimental Studies on Some Zoonotic Diarrheagenic Agents in Albino Rats. AJVS. 2018; 58(1): 196-207. doi:10.5455/ajvs.1176



Vancouver/ICMJE Style

Nossair MA, Ayoub MA, El-Maadawy RS, Shaaban SI. Experimental Studies on Some Zoonotic Diarrheagenic Agents in Albino Rats. AJVS. (2018), [cited December 04, 2023]; 58(1): 196-207. doi:10.5455/ajvs.1176



Harvard Style

Nossair, M. A., Ayoub, . M. A., El-Maadawy, . R. S. & Shaaban, . S. I. (2018) Experimental Studies on Some Zoonotic Diarrheagenic Agents in Albino Rats. AJVS, 58 (1), 196-207. doi:10.5455/ajvs.1176



Turabian Style

Nossair, Mohamed A., Mousa A. Ayoub, Reham S. El-Maadawy, and Sabah I. Shaaban. 2018. Experimental Studies on Some Zoonotic Diarrheagenic Agents in Albino Rats. Alexandria Journal of Veterinary Sciences, 58 (1), 196-207. doi:10.5455/ajvs.1176



Chicago Style

Nossair, Mohamed A., Mousa A. Ayoub, Reham S. El-Maadawy, and Sabah I. Shaaban. "Experimental Studies on Some Zoonotic Diarrheagenic Agents in Albino Rats." Alexandria Journal of Veterinary Sciences 58 (2018), 196-207. doi:10.5455/ajvs.1176



MLA (The Modern Language Association) Style

Nossair, Mohamed A., Mousa A. Ayoub, Reham S. El-Maadawy, and Sabah I. Shaaban. "Experimental Studies on Some Zoonotic Diarrheagenic Agents in Albino Rats." Alexandria Journal of Veterinary Sciences 58.1 (2018), 196-207. Print. doi:10.5455/ajvs.1176



APA (American Psychological Association) Style

Nossair, M. A., Ayoub, . M. A., El-Maadawy, . R. S. & Shaaban, . S. I. (2018) Experimental Studies on Some Zoonotic Diarrheagenic Agents in Albino Rats. Alexandria Journal of Veterinary Sciences, 58 (1), 196-207. doi:10.5455/ajvs.1176





Most Viewed Articles
Most Accessed Articles

  • Assessment of The Efficiency of Some Chemical Disinfectants Used in poultry Farms Against Coccidiosis
    Hamed Abdel tawab Samaha, Yasser Nasr Haggag, Mohammed Al sayed Nossair, Heba Mohammed Habib
    AJVS. 2013; 39(1): 82-90
    » Abstract

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract » doi: 10.5455/ajvs.154650

  • Molecular Characterization of Listeria Species Isolated from Frozen Fish
    Gaber S. Abdellrazeq, Ayman M. Kamar, Samya M. El-Houshy
    AJVS. 2014; 40(1): 1-15
    » Abstract » doi: 10.5455/ajvs.45443

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

  • Most Downloaded
    Top Downloaded Articles

  • Comparative Study of Cellular and Humoral Immune Response to BHV-1 Vaccines in Cattle and Buffalo Calves
    Fayrouz S. Naim; Samy A. Khalil and Helmy A. Torky
    AJVS. 2016; 51(2): 367-373
    » Abstract

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

  • Effect of Excess Fluoride on Reproductive Potentials in Farm Animals (Ovine)
    Ghada H. Abdel-Rahman, Hanaa A. El-Hallawany, Dohreig RA.
    AJVS. 2018; 57(2): 41-57
    » Abstract » doi: 10.5455/ajvs.296364

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Using of Polypropylene Mesh for Hernioplasty in Calves
    Mostafa M. kassam, Mahmoud H. Elkammer, Ahmed S. Korittum, Ali A. Abdel-Wahed
    AJVS. 2014; 40(1): 112-117
    » Abstract » doi: 10.5455/ajvs.47290

  • Most Cited Articles
    Most Cited Articles