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Original Research (Original Article) Open Access


Comparison of Lidocaine and Lidocaine–Neostigmine for Epidural Analgesia in Water Buffalo Calves (Bubalus Bubalis)

Alaa Ghazy, Ayman Atiba, Mustafa Shukry, Tarek Kamal.

Cited by (2)

Abstract
Abstract
The object of this study was to evaluate and compare the effectiveness of epidural injection of lidocaine plus neostigmine and lidocaine alone for perineal analgesia in buffalo. Caudal epidural analgesia was performed in six water buffalo calves at the first inter-coccygeal extradural space. It was produced in all calves by 2% lidocaine alone (0.22 mg/kg) and with 2 weeks intervals, repeated by combination of lidocaine–neostigmine (0.22 mg/kg and 10 µg / kg respectively). Analgesia was tested using deep pin prick stimuli. The time of onset and duration of analgesia, ataxia, heart rate, respiratory rate, and rectal temperature were compared among the two treatments. These parameters were determined before drug administration (baseline 0), at 10 minute intervals thereafter. Both treatments resulted in complete analgesia of the tail, perineum, and the upper parts of the hind limbs. The onset of analgesia was faster, but not significant in lidocaine plus neostigmine compared with lidocaine alone (3 ± 1 and 4 ± 1 minute respectively) (mean ± SD) (P > 0.05). The duration of epidural analgesia was significantly longer in lidocaine plus neostigmine than in lidocaine alone (134 ± 11 and 68 ± 9 minutes respectively) (P <0.05). Both treatments produced mild or moderate motor block. There was no significant alteration in HR, RR, and RT in both treatments. No adverse effects were observed in any of the buffaloe calves. In conclusion, the combination of lidocaine–neostigmine produced analgesia of longer duration than lidocaine. This combination would appear to be recommended for single-dose epidural administration in buffalo calves undergoing long surgical procedures in the perineal region.

Short running title:
Epidural lidocaine and lidocaine-neostigmine in buffalo

Key words: Keywords: Buffaloe calves; perineal analgesia; lidocaine; neostigmine


 
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REFERENCES
Alkan, M., Kaya, K. 2014. Postoperative analgesic effect of epidural neostigmine following caesarean section. Hippokratia 18: 44-49. [Pubmed]    [PMC Free Fulltext]   
Almeida, R. M., EscFobar, A., Maguilnik, S. 2010. Comparison of analgesia provided by lidocaine, lidocaine-morphine or lidocaine-tramadol delivered epidurally in dogs following orchiectomy. Vet. Anaesth. Analg. 37: 542- 549. [DOI via Crossref]    [Pubmed]   
Bigham, A. S., Habibian, S., Ghasemian, F., Layeghi, S. 2010. Caudal epidural of lidocaine, tramadol, and lidocaine-tramadol for epidural anesthesia in cattle. J. Vet. Pharmacol. Ther. 33: 439-443. [DOI via Crossref]    [Pubmed]   
Bouaziz, H., Tong, C., Eisenach, J. C. 1995 Postoperative analgesia from intrathecal neostigmine in sheep. Anesth. Analg. 80: 1140-1144. [Pubmed]   
Cossu, A. P., De Giudici, L. M., Piras, D., Mura, P., Scanu, M., Cossu, M., Saba, M., Finco, G., Brazzi, L. 2015. A systematic review of the effects of adding neostigmine to local anesthetics for neuraxial administration in obstetric anesthesia and analgesia. Int J Obstet Anesth 24, 237-246. [DOI via Crossref]    [Pubmed]   
Day, T. K., Skarda, R. T. 1991. The pharmacological of local anesthetics. Vet. Clin. North Am. Equine Pract. 7, 489-500. [Pubmed]   
Demiraran, Y., Kocaman, B., Akman, R. Y. 2005. A comparison of the postoperative analgesic efficacy of single dose epidural tramadol versus morphine in children. Br. J. Anaesth. 95, 510-513. [DOI via Crossref]    [Pubmed]   
Derossi R., Módolo, T. J. C., Maciel, F. B., Pagliosa, R.C. 2013. Efficacy of epidural lidocaine combined with tramadol or neostigmine on perineal analgesia in the horse. Equine Vet. J. 45: 497-502. [DOI via Crossref]    [Pubmed]   
Grubb, T. L., Riebold, T. W., Huber, M. J. 1992. Comparison of lidocaine, xylazine, and xylazine/lidobcaine for caudal epidural analgesia in horses. J. Am. Vet. Med. Assoc. 201:1187-1190. [Pubmed]   
Hall, L. W., Clarke, K. W., Tri-m, C. M. 2001. Veterinary Anaesthesia. 10th ed. W. B. Saunders, London. pp. 315-339. [DOI via Crossref]    [Pubmed]   
Harjai, M., Chandra, G., Bhatia, V.K., Singh, D., Bhaskar, P. 2010. A Comparative Study of Two Different Doses of Epidural Neostigmine Coadministered with Lignocaine for Post Operative Analgesia and Sedation. Journal of Anaesthesiology, Clinical Pharmacology. 26(4):461-464. [Pubmed]    [PMC Free Fulltext]   
Hood, D. D., Eisenach, J. C., Tuttle, R. 1995. Phase I safety assessment of intrathecal neostigmine methylsulfate in humans. Anesthesiol. 82:331-343. [DOI via Crossref]   
Hugar, B., Gupta O. P., Singh, G. R. 2000. Studies on the clinical effects of medetomidine as a preanaesthetic to ketamine anaesthesia in goats. Indian Vet. J. 77: 678-682
Koichev, K., Golemanov, D., Houbenov, H., Aminokov, B. 1988. Experimental study on the effect of “Domosedan” in sheep and cattle. J. Associat. Vet. Anesthet. 15: 114-116. [DOI via Crossref]   
Kumar, P., Rudra, A., Pan, A.K. and Acharya, A. 2005. Caudal additives in pediatrics: a comparison among midazolam, ketamine, and neostigmine coadministered with bupivacaine. Anesth. Analg. 101: 69-73. [DOI via Crossref]    [Pubmed]   
Lauretti, G. R., de Oliveira, R., Reis, M.P., Juliao, M. C. C. Pereira, N. L. 1999. Study of three different doses of epidural neostigmine coadministered with lidocaine for postoperative analgesia. Anesthesiol. 90: 1534- 1538. [DOI via Crossref]   
Marucio, R. L., Luna, S. P. L., Teixeira, F., Minto, B. W., Hatschbach, E. 2008. Postoperative analgesic effects of epidural administration of neostigmine alone or in combination with morphine in ovariohysterectomized dogs. Am. J. Vet. Res. 69: 854-860. [DOI via Crossref]    [Pubmed]   
Marucio, R. L., Monteiro, E. R., Moroz, L. R., Fantoni, D.T. 2014. Postoperative analgesic effects of epidural administration of neostigmine alone or in combination with morphine in dogs undergoing orthopedic surgery of the pelvic limbs. Am. J. Vet. Res. 75: 956-963. [DOI via Crossref]    [Pubmed]   
Memis, D., Turan, A., Karamanliog˘ lu, B., Kaya, G., Sut, N., Pamukcu, Z. 2003. Caudal neostigmine for postoperative analgesia in paediatric surgery. Pediatr. Anaesth. 13: 324-328. [DOI via Crossref]    [Pubmed]   
Mirakhur, K. K., Sobti, V. K., Nigam, J. M. 1984. Effect of thiopentone anaesthesia on plas-ma catecholamine and cortisol in buffalo calves (Bubalus bubalis). Indian J. Vet. Surg. 3: 86-88.
Moulvi B. A., Parrah J. D., Kalim M. O., Athar H., Dedmari F. H. 2011. Haemato-biochemical Response to Lignocaine alone or in Combination with Xylazine for Epidural Analgesia in Cow Calves. J.Advan.Vet. Res. 1:17-20.
Muir, W. W., Hubbell, J. A. E., Sk-arda, R. T., Bednarski, R. M. 2000. Handbook of Veterinary Anesthesia, 3rd ed. Mosby, St. Louis. pp. 57-81.
Natalini, C. C., Robinson, E. P. 2000. Evaluation of the analgesic effects of epidurally administered morphine, alfentanil, butorphanol, tramadol, and U50488H in horses. Am. J. Vet. Res. 61: 1579-1586. [DOI via Crossref]    [Pubmed]   
Sharda, R., Dutta, G. K., Tiwari, S. K., Sharda, N. 2008. Effect of xylazine, Ketamine and their combination ass epidural anaesthesia in buffalo calves. Indian Vet. J.85: 608-610.
Singh, P., Pratap, K., Amarpal, Kinjavdekar, P., Aithal, H. P., Singh, G. R. 2005. Effects of xylazine, lignocaine and their combination for lumber epidural analgesia in water buffalo calves (Bubalus bubalis). J. South African Vet. Associat.76: 151-158. [DOI via Crossref]    [Pubmed]   
Thurmon, J.C., Tranquilli, W.J., Benson, G.J. 1996. Lumb & JonesÂ’ Veterinary Anesthesia, 3rd ed. Williams & Wilkins, Baltimore. pp. 479-514.
Wagner, A. E., Miur, W., Hinchoff, K. W. 1991. Cardiopul-monary effects of xylazine and detomidine in horses. Am. J. Vet. Re. 52: 651-659. [Pubmed]   
Wilder-Smith, C. H., Wilder-Smith, O. H. G., Farschtschian, M., Naji, P. 1998. Preoperative adjuvant epidural tramadol: the effect of different doses on postoperative analgesia and pain processing. Acta Anaesthesiol. Scand. 42: 299-305. [DOI via Crossref]    [Pubmed]   

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Vet World 2016; 9(12): 1450.

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Evaluation of Analgesic Effect of Caudal Epidural Tramadol, Tramadol-Lidocaine, and Lidocaine in Water Buffalo Calves (Bubalus bubalis)
Veterinary Medicine International 2015; 2015(): 1.

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How to Cite this Article
Pubmed Style

Ghazy A, Atiba A, Shukry M, Kamal T. Comparison of Lidocaine and Lidocaine–Neostigmine for Epidural Analgesia in Water Buffalo Calves (Bubalus Bubalis). AJVS. 2015; 46(1): 177-181. doi:10.5455/ajvs.198171


Web Style

Ghazy A, Atiba A, Shukry M, Kamal T. Comparison of Lidocaine and Lidocaine–Neostigmine for Epidural Analgesia in Water Buffalo Calves (Bubalus Bubalis). http://www.alexjvs.com//?mno=198171 [Access: January 18, 2018]. doi:10.5455/ajvs.198171


AMA (American Medical Association) Style

Ghazy A, Atiba A, Shukry M, Kamal T. Comparison of Lidocaine and Lidocaine–Neostigmine for Epidural Analgesia in Water Buffalo Calves (Bubalus Bubalis). AJVS. 2015; 46(1): 177-181. doi:10.5455/ajvs.198171



Vancouver/ICMJE Style

Ghazy A, Atiba A, Shukry M, Kamal T. Comparison of Lidocaine and Lidocaine–Neostigmine for Epidural Analgesia in Water Buffalo Calves (Bubalus Bubalis). AJVS. (2015), [cited January 18, 2018]; 46(1): 177-181. doi:10.5455/ajvs.198171



Harvard Style

Ghazy, A., Atiba, A., Shukry, M. & Kamal, T. (2015) Comparison of Lidocaine and Lidocaine–Neostigmine for Epidural Analgesia in Water Buffalo Calves (Bubalus Bubalis). AJVS, 46 (1), 177-181. doi:10.5455/ajvs.198171



Turabian Style

Ghazy, Alaa, Ayman Atiba, Mustafa Shukry, and Tarek Kamal. 2015. Comparison of Lidocaine and Lidocaine–Neostigmine for Epidural Analgesia in Water Buffalo Calves (Bubalus Bubalis). Alexandria Journal of Veterinary Sciences, 46 (1), 177-181. doi:10.5455/ajvs.198171



Chicago Style

Ghazy, Alaa, Ayman Atiba, Mustafa Shukry, and Tarek Kamal. "Comparison of Lidocaine and Lidocaine–Neostigmine for Epidural Analgesia in Water Buffalo Calves (Bubalus Bubalis)." Alexandria Journal of Veterinary Sciences 46 (2015), 177-181. doi:10.5455/ajvs.198171



MLA (The Modern Language Association) Style

Ghazy, Alaa, Ayman Atiba, Mustafa Shukry, and Tarek Kamal. "Comparison of Lidocaine and Lidocaine–Neostigmine for Epidural Analgesia in Water Buffalo Calves (Bubalus Bubalis)." Alexandria Journal of Veterinary Sciences 46.1 (2015), 177-181. Print. doi:10.5455/ajvs.198171



APA (American Psychological Association) Style

Ghazy, A., Atiba, A., Shukry, M. & Kamal, T. (2015) Comparison of Lidocaine and Lidocaine–Neostigmine for Epidural Analgesia in Water Buffalo Calves (Bubalus Bubalis). Alexandria Journal of Veterinary Sciences, 46 (1), 177-181. doi:10.5455/ajvs.198171





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