E-ISSN 2536-9520 | ISSN 1110-2047
 
2025, Vol: 85
85Current Volume Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Article 


Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders

Fadwa M. Othman, Mahmud I. Mohamed, Diya’ud Din A. El-badry, Mona H. Shaker, Mohamed Hosam R. Kotb, Helmy A. Turky.


Abstract
This study aimed to select a potent and safe antimycotic as additive to cryodiluents of sheep frozen semen. Semen samples were collected from 6 Barki rams and processed for cryopreservation after adding different concentrations of griseovulvin, clotrimazole, nystatin, fluconazole and amphotricin-B to semen diluent. Sensitivity of Candida albicans and Cryptococcus neoformans to antimycotic drugs were studied. Results showed that fluconazole and nystatin (at dose not higher than 50 mg/L) had no deleterious effect on sheep semen freezability. Higher doses of amphotricin-B and griseofulvin resulted in drastic deterioration of frozen semen quality. Candida albicans and Cryptococcus neoformans were sensitive to fluconazole and amphotricin-B and resistant to lower concentrations of griseovulvin and clotrimazole. Conclusively, addition of fluconazole to sheep semen diluent has a benefit of improving the quality of yeast contaminated sperm with no bad effect on the frozen-thawed semen quality.

Key words: : anti-mycotic, amphotricin-B, Candida, Cryptococcus, frozen semen, sheep


 
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How to Cite this Article
Pubmed Style

Othman FM, Mohamed MI, El-badry DDA, Shaker MH, Kotb MHR, Turky HA. Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. AJVS. 0; 0(0): -.

Web Style

Othman FM, Mohamed MI, El-badry DDA, Shaker MH, Kotb MHR, Turky HA. Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. https://www.alexjvs.com/?mno=202267 [Access: March 25, 2025].

AMA (American Medical Association) Style

Othman FM, Mohamed MI, El-badry DDA, Shaker MH, Kotb MHR, Turky HA. Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. AJVS. 0; 0(0): -.


Vancouver/ICMJE Style

Othman FM, Mohamed MI, El-badry DDA, Shaker MH, Kotb MHR, Turky HA. Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. AJVS. (0), [cited March 25, 2025]; 0(0): -.


Harvard Style

Othman, F. M., Mohamed, . M. I., El-badry, . D. D. A., Shaker, . M. H., Kotb, . M. H. R. & Turky, . H. A. (0) Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. AJVS, 0 (0), -.


Turabian Style

Othman, Fadwa M., Mahmud I. Mohamed, Diya’ud Din A. El-badry, Mona H. Shaker, Mohamed Hosam R. Kotb, and Helmy A. Turky. 0. Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. Alexandria Journal of Veterinary Sciences, 0 (0), -.


Chicago Style

Othman, Fadwa M., Mahmud I. Mohamed, Diya’ud Din A. El-badry, Mona H. Shaker, Mohamed Hosam R. Kotb, and Helmy A. Turky. "Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders." Alexandria Journal of Veterinary Sciences 0 (0), -.


MLA (The Modern Language Association) Style

Othman, Fadwa M., Mahmud I. Mohamed, Diya’ud Din A. El-badry, Mona H. Shaker, Mohamed Hosam R. Kotb, and Helmy A. Turky. "Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders." Alexandria Journal of Veterinary Sciences 0.0 (0), -. Print.


APA (American Psychological Association) Style

Othman, F. M., Mohamed, . M. I., El-badry, . D. D. A., Shaker, . M. H., Kotb, . M. H. R. & Turky, . H. A. (0) Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. Alexandria Journal of Veterinary Sciences, 0 (0), -.




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    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110 ... Read more.



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