E-ISSN 2536-9520 | ISSN 1110-2047
 
2024, Vol: 83
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Original Article 


Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders

Fadwa M. Othman, Mahmud I. Mohamed, Diya’ud Din A. El-Badry, Mona H. Shaker, Mohamed hosam R. Kotb, Helmy A. Turky.


Abstract
This study aimed to select a potent and safe antimycotic as additive to cryodiluents of sheep frozen semen. Semen samples were collected from 6 Barki rams and processed for cryopreservation after adding different concentrations of griseovulvin, clotrimazole, nystatin, fluconazole and amphotricin-B to semen diluent. Sensitivity of Candida albicans and Cryptococcus neoformans to antimycotic drugs were studied. Results showed that fluconazole and nystatin (at dose not higher than 50 mg/L) had no deleterious effect on sheep semen freezability. Higher doses of amphotricin-B and griseofulvin resulted in drastic deterioration of frozen semen quality. Candida albicans and Cryptococcus neoformans were sensitive to fluconazole and amphotricin-B and resistant to lower concentrations of griseovulvin and clotrimazole. Conclusively, addition of fluconazole to sheep semen diluent has a benefit of improving the quality of yeast contaminated sperm with no bad effect on the frozen-thawed semen quality.

Key words: : anti-mycotic, amphotricin-B, Candida, Cryptococcus, frozen semen, sheep


 
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Pubmed Style

Fadwa M. Othman, Mahmud I. Mohamed, Diya’ud Din A. El-Badry, Mona H. Shaker, Mohamed hosam R. Kotb, Helmy A. Turky. Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. AJVS. 0; 0(0): -.

Web Style

Fadwa M. Othman, Mahmud I. Mohamed, Diya’ud Din A. El-Badry, Mona H. Shaker, Mohamed hosam R. Kotb, Helmy A. Turky. Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. https://www.alexjvs.com/?mno=202267 [Access: September 12, 2024].

AMA (American Medical Association) Style

Fadwa M. Othman, Mahmud I. Mohamed, Diya’ud Din A. El-Badry, Mona H. Shaker, Mohamed hosam R. Kotb, Helmy A. Turky. Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. AJVS. 0; 0(0): -.


Vancouver/ICMJE Style

Fadwa M. Othman, Mahmud I. Mohamed, Diya’ud Din A. El-Badry, Mona H. Shaker, Mohamed hosam R. Kotb, Helmy A. Turky. Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. AJVS. (0), [cited September 12, 2024]; 0(0): -.


Harvard Style

Fadwa M. Othman, Mahmud I. Mohamed, Diya’ud Din A. El-Badry, Mona H. Shaker, Mohamed hosam R. Kotb, Helmy A. Turky (0) Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. AJVS, 0 (0), -.


Turabian Style

Fadwa M. Othman, Mahmud I. Mohamed, Diya’ud Din A. El-Badry, Mona H. Shaker, Mohamed hosam R. Kotb, Helmy A. Turky. 0. Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. Alexandria Journal of Veterinary Sciences, 0 (0), -.


Chicago Style

Fadwa M. Othman, Mahmud I. Mohamed, Diya’ud Din A. El-Badry, Mona H. Shaker, Mohamed hosam R. Kotb, Helmy A. Turky. "Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders." Alexandria Journal of Veterinary Sciences 0 (0), -.


MLA (The Modern Language Association) Style

Fadwa M. Othman, Mahmud I. Mohamed, Diya’ud Din A. El-Badry, Mona H. Shaker, Mohamed hosam R. Kotb, Helmy A. Turky. "Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders." Alexandria Journal of Veterinary Sciences 0.0 (0), -. Print.


APA (American Psychological Association) Style

Fadwa M. Othman, Mahmud I. Mohamed, Diya’ud Din A. El-Badry, Mona H. Shaker, Mohamed hosam R. Kotb, Helmy A. Turky (0) Efficacy and safety of different antimycotic formulas used in sheep frozen semen extenders. Alexandria Journal of Veterinary Sciences, 0 (0), -.




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    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110 ... Read more.



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