Abstract
To determine the general anesthetic effects and evaluate the hemato-biochemial and clinico-physiological parameters of ketamine HCl and telazol on stray dogs. Sixteen apparently healthy dogs without any abnormalities were used in this study. The study was carried out as a crossover experimental trial with a 7-day interval between the two treatments. Ketamine HCl and telazol were administered intravenously (IV) as a TIVA (Total Intra-Venous Anesthesia) at a dose of 5 mg/kg and 6 mg/kg respectively, with xylazine HCl as a preanesthetic medication at dose of 1mg/kg bwt. Baseline blood samples were collected in both treatments before injection of the preanesthetic medication with five minutes, then four blood samples were collected at different stages along the experiment (15, 30, 60 and 90) minutes after treatments for the hemato-biochemical evaluation, also clinico-physiological observations were recorded at the same times with blood sampling. Both ketamine HCl and telazol had no clinically significant effect on the clinico-physiological parameters and also hemato-biochemical values of the dogs. Both drugs can be used as TIVA (Total Intra-Venous Anesthesia) in dogs. This could be an option for induction and surgical procedures in dogs. However, telazol can be used only without muscle relaxant. Telazol recorded the longest duration of anesthesia.