E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Research (Original Article) 


The Effects of Topical Dimethyle Sulfoxide on Second-Degree Burn Wound Healing in Dogs

Ayman Atiba and Alaa Ghazy.

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  • Abstract
    Burn injury is a major cause of death and disability worldwide. Healing of burn wounds still remains a challenge to modern medicine. The aim of this study was to investigate the effects of Dimethyl sulfoxide (DMSO) on a second-degree burn wounds and compare it with that of silver sulfadiazine (SSD) 1% cream in dogs. A standard deep second-degree burn wound was produced, five dogs, each dog have three groups, DMSO, SSD and control (untreated). The efficacy of treatment was assessed based on the healing percentage of the wound, time to complete wound healing and the degree of inflammation. Wound contraction was higher in the DMSO group than both SSD and the control group. It was significantly higher in the DMSO group than the control group on days 21 and 24 (P < 0.05). The mean times for wound complete closure were 24.4 ± 2.23 and 25.7 ± 2.31 days for DMSO and SSD, respectively, being shorter for DMSO but not significantly (P> 0.05). Clinically, inflammatory reaction was less in DMSO group than the control group. Topical application of DMSO has significant positive effects on the healing of burn wounds in a dog model.

    Key words: DMSO, Dog, Burn, Wound-Healing


     
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    How to Cite this Article
    Pubmed Style

    Ayman Atiba and Alaa Ghazy. The Effects of Topical Dimethyle Sulfoxide on Second-Degree Burn Wound Healing in Dogs. AJVS. 2015; 45(1): 6-12. doi:10.5455/ajvs.177583


    Web Style

    Ayman Atiba and Alaa Ghazy. The Effects of Topical Dimethyle Sulfoxide on Second-Degree Burn Wound Healing in Dogs. http://www.alexjvs.com/?mno=177583 [Access: August 21, 2018]. doi:10.5455/ajvs.177583


    AMA (American Medical Association) Style

    Ayman Atiba and Alaa Ghazy. The Effects of Topical Dimethyle Sulfoxide on Second-Degree Burn Wound Healing in Dogs. AJVS. 2015; 45(1): 6-12. doi:10.5455/ajvs.177583



    Vancouver/ICMJE Style

    Ayman Atiba and Alaa Ghazy. The Effects of Topical Dimethyle Sulfoxide on Second-Degree Burn Wound Healing in Dogs. AJVS. (2015), [cited August 21, 2018]; 45(1): 6-12. doi:10.5455/ajvs.177583



    Harvard Style

    Ayman Atiba and Alaa Ghazy (2015) The Effects of Topical Dimethyle Sulfoxide on Second-Degree Burn Wound Healing in Dogs. AJVS, 45 (1), 6-12. doi:10.5455/ajvs.177583



    Turabian Style

    Ayman Atiba and Alaa Ghazy. 2015. The Effects of Topical Dimethyle Sulfoxide on Second-Degree Burn Wound Healing in Dogs. Alexandria Journal of Veterinary Sciences, 45 (1), 6-12. doi:10.5455/ajvs.177583



    Chicago Style

    Ayman Atiba and Alaa Ghazy. "The Effects of Topical Dimethyle Sulfoxide on Second-Degree Burn Wound Healing in Dogs." Alexandria Journal of Veterinary Sciences 45 (2015), 6-12. doi:10.5455/ajvs.177583



    MLA (The Modern Language Association) Style

    Ayman Atiba and Alaa Ghazy. "The Effects of Topical Dimethyle Sulfoxide on Second-Degree Burn Wound Healing in Dogs." Alexandria Journal of Veterinary Sciences 45.1 (2015), 6-12. Print. doi:10.5455/ajvs.177583



    APA (American Psychological Association) Style

    Ayman Atiba and Alaa Ghazy (2015) The Effects of Topical Dimethyle Sulfoxide on Second-Degree Burn Wound Healing in Dogs. Alexandria Journal of Veterinary Sciences, 45 (1), 6-12. doi:10.5455/ajvs.177583





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