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Original Article 


Distribution of Paraoxonase-1 enzyme Activity in some Camel's Tissues

Eman M. Abd El maksoud, Nabil M.Taha, Abd El Wahab A. Mandour, Mohamed A. Lebda, Amany M. El-Mmorshedy.

Abstract
Paraoxonase-1 (PON1,aryldialkylphosphatase) is a calcium-dependent esterase enzyme synthesized in the liver and it is mainly associated with a high density lipoprotein (HDL).This study aimed to investigate the PON1 enzyme activities in male camel's serum& tissues and its distribution among camel tissues (liver, heart and kidney) in immature and mature camels. PON1 activity in serum (32 dromedary camels, 17one of them immature ≤ 5 years; 15 one mature > 5years) were 115.89 � 11.37 U/L and 114.43 � 11.87 U/L, respectively. The results showed that PON1 was highly distributed in the liver then kidney and heart tissues in immature camels (2.74 � 0.42, 1.66 � 0.14, 0.017 � 0.005 U/g) as well in mature camels (2.41 � 0.29, 1.41 � 0.12, 0.019 � 0.005 U/g), respectively. Also, Glutathione peroxidase (GPx) and Superoxide dismutase (SOD) were highly distributed in liver then kidney and heart tissues. Moreover, GPx activity in liver was higher with increased camel's age. PON1 is correlated positively with GPx & SOD and HDL-c but negatively correlated with MDA and total cholesterol. Furthermore, was found positive correlation between total cholesterol and LDL-c in serum and hepatic tissues.

Key words: Camel, Paraoxonase-1, Superoxide dismutase, Glutathione peroxidase, Malondialdehyde


 
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Pubmed Style

Eman M. Abd El maksoud, Nabil M.Taha, Abd El Wahab A. Mandour, Mohamed A. Lebda, Amany M. El-Mmorshedy. Distribution of Paraoxonase-1 enzyme Activity in some Camel's Tissues. AJVS. 2016; 51(2): 239-244. doi:10.5455/ajvs.207546

Web Style

Eman M. Abd El maksoud, Nabil M.Taha, Abd El Wahab A. Mandour, Mohamed A. Lebda, Amany M. El-Mmorshedy. Distribution of Paraoxonase-1 enzyme Activity in some Camel's Tissues. https://www.alexjvs.com/?mno=207546 [Access: December 03, 2023]. doi:10.5455/ajvs.207546

AMA (American Medical Association) Style

Eman M. Abd El maksoud, Nabil M.Taha, Abd El Wahab A. Mandour, Mohamed A. Lebda, Amany M. El-Mmorshedy. Distribution of Paraoxonase-1 enzyme Activity in some Camel's Tissues. AJVS. 2016; 51(2): 239-244. doi:10.5455/ajvs.207546


Vancouver/ICMJE Style

Eman M. Abd El maksoud, Nabil M.Taha, Abd El Wahab A. Mandour, Mohamed A. Lebda, Amany M. El-Mmorshedy. Distribution of Paraoxonase-1 enzyme Activity in some Camel's Tissues. AJVS. (2016), [cited December 03, 2023]; 51(2): 239-244. doi:10.5455/ajvs.207546


Harvard Style

Eman M. Abd El maksoud, Nabil M.Taha, Abd El Wahab A. Mandour, Mohamed A. Lebda, Amany M. El-Mmorshedy (2016) Distribution of Paraoxonase-1 enzyme Activity in some Camel's Tissues. AJVS, 51 (2), 239-244. doi:10.5455/ajvs.207546


Turabian Style

Eman M. Abd El maksoud, Nabil M.Taha, Abd El Wahab A. Mandour, Mohamed A. Lebda, Amany M. El-Mmorshedy. 2016. Distribution of Paraoxonase-1 enzyme Activity in some Camel's Tissues. Alexandria Journal of Veterinary Sciences, 51 (2), 239-244. doi:10.5455/ajvs.207546


Chicago Style

Eman M. Abd El maksoud, Nabil M.Taha, Abd El Wahab A. Mandour, Mohamed A. Lebda, Amany M. El-Mmorshedy. "Distribution of Paraoxonase-1 enzyme Activity in some Camel's Tissues." Alexandria Journal of Veterinary Sciences 51 (2016), 239-244. doi:10.5455/ajvs.207546


MLA (The Modern Language Association) Style

Eman M. Abd El maksoud, Nabil M.Taha, Abd El Wahab A. Mandour, Mohamed A. Lebda, Amany M. El-Mmorshedy. "Distribution of Paraoxonase-1 enzyme Activity in some Camel's Tissues." Alexandria Journal of Veterinary Sciences 51.2 (2016), 239-244. Print. doi:10.5455/ajvs.207546


APA (American Psychological Association) Style

Eman M. Abd El maksoud, Nabil M.Taha, Abd El Wahab A. Mandour, Mohamed A. Lebda, Amany M. El-Mmorshedy (2016) Distribution of Paraoxonase-1 enzyme Activity in some Camel's Tissues. Alexandria Journal of Veterinary Sciences, 51 (2), 239-244. doi:10.5455/ajvs.207546




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    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110 ... Read more.



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