Multimodal Approach to Surgical Pain Management in Weaner Pigs: A Clinical Trial

Emmanuella A.O. Sogebi; Oludele A. Makinde; Ann I. Cliff; Sulaimon Koleoso; Fakilahyel Mshelbwala; Johnny O. Olukunle

doi:10.5455/ajvs.28821

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Original Article
Online Published: 31 Jan 2021

AJVS. 2021; 70(1): 151-157

doi: 10.5455/ajvs.28821

Multimodal Approach to Surgical Pain Management in Weaner Pigs: A Clinical Trial

Emmanuella A.o. Sogebi, Oludele A. Makinde, Ann I. Cliff, Sulaimon Koleoso, Fakilahyel Mshelbwala, Johnny O. Olukunle.

Abstract
The use of two or more classes of analgesics that act by different modes of action within the pain pathways, leading to additive or, even synergistic analgesia, even synergistic analgesia has been documented as nociceptive information is known to be transmitted tthrough numerous anatomical pathways and by multiple substances. Three patients were scheduled for ovariohysterectomy (OVH), resection and anastomosis and right radical nephrectomy. They received 0.05mgkg-1 1% atropine and 0.01mgkg-1 dexmedetomidine as premedicants; induced and maintained with ketamine 10mgkg-1and 5mgkghr-1 respectively, 200µgkg-1 butorphanol and 0.03mgkg-1 buprenorphine as analgesics and 5mgkg-1 meloxicam post-operatively . Anaesthestic indices (duration and quality of anaesthesia, analgesia and the quality of induction) were recorded. Physiological variables (heart rate, respiratory rate, pulse rate, peripheral capillary oxygen saturation and rectal temperature) were measured at 0, thereafter at 15 minutes interval post treatment for one hour. Observed parameters were statistically analyzed by using independent sample t test. P<0.05 was considered statistically significant. Quality of induction was fair, anaesthesia lasted for 113.3 ± 5.1 minues, quality of analgesia was very good and recovery time was 2.8 ± 0.2minutes.No significant differences were observed in the heart rate (P=0.55), pulse rate (P=0.71), peripheral capillary oxygen saturation (P=0.50) and rectal temperature (P=0.74); but with a significant difference in the respiratory rate (P=0.03).Anaemia was reported in all three patients.

Key words: Clinical Trial, Multimodal, Surgical Pain Management, Synergy, Piglets

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How to Cite this Article

Pubmed Style

Sogebi EA, Makinde OA, Cliff AI, Koleoso S, Mshelbwala F, Olukunle JO. Multimodal Approach to Surgical Pain Management in Weaner Pigs: A Clinical Trial. AJVS. 2021; 70(1): 151-157. doi:10.5455/ajvs.28821

Web Style

Sogebi EA, Makinde OA, Cliff AI, Koleoso S, Mshelbwala F, Olukunle JO. Multimodal Approach to Surgical Pain Management in Weaner Pigs: A Clinical Trial. https://www.alexjvs.com/?mno=28821 [Access: May 04, 2025]. doi:10.5455/ajvs.28821

AMA (American Medical Association) Style

Sogebi EA, Makinde OA, Cliff AI, Koleoso S, Mshelbwala F, Olukunle JO. Multimodal Approach to Surgical Pain Management in Weaner Pigs: A Clinical Trial. AJVS. 2021; 70(1): 151-157. doi:10.5455/ajvs.28821

Vancouver/ICMJE Style

Sogebi EA, Makinde OA, Cliff AI, Koleoso S, Mshelbwala F, Olukunle JO. Multimodal Approach to Surgical Pain Management in Weaner Pigs: A Clinical Trial. AJVS. (2021), [cited May 04, 2025]; 70(1): 151-157. doi:10.5455/ajvs.28821

Harvard Style

Sogebi, E. A., Makinde, . O. A., Cliff, . A. I., Koleoso, . S., Mshelbwala, . F. & Olukunle, . J. O. (2021) Multimodal Approach to Surgical Pain Management in Weaner Pigs: A Clinical Trial. AJVS, 70 (1), 151-157. doi:10.5455/ajvs.28821

Turabian Style

Sogebi, Emmanuella A.o., Oludele A. Makinde, Ann I. Cliff, Sulaimon Koleoso, Fakilahyel Mshelbwala, and Johnny O. Olukunle. 2021. Multimodal Approach to Surgical Pain Management in Weaner Pigs: A Clinical Trial. Alexandria Journal of Veterinary Sciences, 70 (1), 151-157. doi:10.5455/ajvs.28821

Chicago Style

Sogebi, Emmanuella A.o., Oludele A. Makinde, Ann I. Cliff, Sulaimon Koleoso, Fakilahyel Mshelbwala, and Johnny O. Olukunle. "Multimodal Approach to Surgical Pain Management in Weaner Pigs: A Clinical Trial." Alexandria Journal of Veterinary Sciences 70 (2021), 151-157. doi:10.5455/ajvs.28821

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

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