E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Research (Original Article) 


Induced Acute Renal Failure (Injury) by Administration of Ethylene Glycol (Antifreeze) in Cats

Zeinab K.Ebrahim, Ali M. Metwally, Magda S. Elsayed, Sabreene M. Gemeaa.

Abstract
Etheylene glycol (EG) poisoning is highly dangerous in cats and a small dose of it could cause signs which are initially non-specific and may be easily missed. So,our study was preformed to determine the various effects of EG administration on cats. 10 cats of both sexes aging 1-3 years old were included in this experimental study. Cats were examined before starting the experiment clinically , physically and ultrasonographically to ensure their soundness, then EG was administrated at a dose of 1.4 ml/kg b.wt. orally by using of sterile syringe.clinical signs started with in 12 hours after adminstraion and 4 cases were died in the 2nd day after ingestion and the remaining 6 cats were followed up to 5th day of EG administration. Clinical, physical, , urine, ultrasonographic and post-mortem examinations were preformed on each cat before EG ingestion and on the 2nd and 5th day after EG ingestion . In addition, Blood samples wre collected from each cat for hematological and serum biochemical analysis. Our results revealed that, clinically the cats were depressed ,anorexic, unwilling to move with decreased rectal temperature and pulse rate while the respiratory rate was sigificantly increased at the 5th day of EG ingestion. Hematological analysis showed a significant increase of erythrocytic count while hemoglobin and PCV levels were significantly decreased at the 5th day of the experiment.The total leucocytic count was significanlty increased with significant neutrophilia and lymphocytopenia at the end of the experiment. Serum analysis of these cats showed azotemia, reduction in calcium, potassium and chloride with elevated phosphorus, sodium and magnesium levels. Urinalysis showed calcium oxalate crystalluria which could be noticed shortly after EG ingestion. It could be conculded that ethylene glycol ingestion could cause a sever renal damage in cats which may be fatal and methods of prevention of its ingestion by cats should be applied to avoid its serious effects.

Key words: ethylene glycol, cat, induced renal injury


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Zeinab K.Ebrahim
Articles by Ali M. Metwally
Articles by Magda S. Elsayed
Articles by Sabreene M. Gemeaa
on Google
on Google Scholar
Article Statistics
 Viewed: 1147
Downloaded: 67


How to Cite this Article
Pubmed Style

K.Ebrahim Z, Metwally AM, Elsayed MS, Gemeaa SM. Induced Acute Renal Failure (Injury) by Administration of Ethylene Glycol (Antifreeze) in Cats. AJVS. 2019; 63(1): 51-58. doi:10.5455/ajvs.61454


Web Style

K.Ebrahim Z, Metwally AM, Elsayed MS, Gemeaa SM. Induced Acute Renal Failure (Injury) by Administration of Ethylene Glycol (Antifreeze) in Cats. http://www.alexjvs.com/?mno=61454 [Access: February 08, 2020]. doi:10.5455/ajvs.61454


AMA (American Medical Association) Style

K.Ebrahim Z, Metwally AM, Elsayed MS, Gemeaa SM. Induced Acute Renal Failure (Injury) by Administration of Ethylene Glycol (Antifreeze) in Cats. AJVS. 2019; 63(1): 51-58. doi:10.5455/ajvs.61454



Vancouver/ICMJE Style

K.Ebrahim Z, Metwally AM, Elsayed MS, Gemeaa SM. Induced Acute Renal Failure (Injury) by Administration of Ethylene Glycol (Antifreeze) in Cats. AJVS. (2019), [cited February 08, 2020]; 63(1): 51-58. doi:10.5455/ajvs.61454



Harvard Style

K.Ebrahim, Z., Metwally, . A. M., Elsayed, . M. S. & Gemeaa, . S. M. (2019) Induced Acute Renal Failure (Injury) by Administration of Ethylene Glycol (Antifreeze) in Cats. AJVS, 63 (1), 51-58. doi:10.5455/ajvs.61454



Turabian Style

K.Ebrahim, Zeinab, Ali M. Metwally, Magda S. Elsayed, and Sabreene M. Gemeaa. 2019. Induced Acute Renal Failure (Injury) by Administration of Ethylene Glycol (Antifreeze) in Cats. Alexandria Journal of Veterinary Sciences, 63 (1), 51-58. doi:10.5455/ajvs.61454



Chicago Style

K.Ebrahim, Zeinab, Ali M. Metwally, Magda S. Elsayed, and Sabreene M. Gemeaa. "Induced Acute Renal Failure (Injury) by Administration of Ethylene Glycol (Antifreeze) in Cats." Alexandria Journal of Veterinary Sciences 63 (2019), 51-58. doi:10.5455/ajvs.61454



MLA (The Modern Language Association) Style

K.Ebrahim, Zeinab, Ali M. Metwally, Magda S. Elsayed, and Sabreene M. Gemeaa. "Induced Acute Renal Failure (Injury) by Administration of Ethylene Glycol (Antifreeze) in Cats." Alexandria Journal of Veterinary Sciences 63.1 (2019), 51-58. Print. doi:10.5455/ajvs.61454



APA (American Psychological Association) Style

K.Ebrahim, Z., Metwally, . A. M., Elsayed, . M. S. & Gemeaa, . S. M. (2019) Induced Acute Renal Failure (Injury) by Administration of Ethylene Glycol (Antifreeze) in Cats. Alexandria Journal of Veterinary Sciences, 63 (1), 51-58. doi:10.5455/ajvs.61454





Most Viewed Articles
  • Assessment of The Efficiency of Some Chemical Disinfectants Used in poultry Farms Against Coccidiosis
    Hamed Abdel tawab Samaha, Yasser Nasr Haggag, Mohammed Al sayed Nossair, Heba Mohammed Habib
    AJVS. 2013; 39(1): 82-90
    » Abstract & References

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract & References » doi: 10.5455/ajvs.154650

  • Molecular Characterization of Listeria Species Isolated from Frozen Fish
    Gaber S. Abdellrazeq, Ayman M. Kamar, Samya M. El-Houshy
    AJVS. 2014; 40(1): 1-15
    » Abstract & References » doi: 10.5455/ajvs.45443

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232

  • Most Downloaded
  • Comparative Study of Cellular and Humoral Immune Response to BHV-1 Vaccines in Cattle and Buffalo Calves
    Fayrouz S. Naim; Samy A. Khalil and Helmy A. Torky
    AJVS. 2016; 51(2): 367-373
    » Abstract

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333

  • Using of Polypropylene Mesh for Hernioplasty in Calves
    Mostafa M. kassam, Mahmoud H. Elkammer, Ahmed S. Korittum, Ali A. Abdel-Wahed
    AJVS. 2014; 40(1): 112-117
    » Abstract & References » doi: 10.5455/ajvs.47290

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract & References » doi: 10.5455/ajvs.154650

  • Most Cited Articles
  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract & References » doi: 10.5455/ajvs.48333
    Cited : 8 times [Click to see citing articles]

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract & References » doi: 10.5455/ajvs.48232
    Cited : 7 times [Click to see citing articles]

  • Detection of Molecular Characterization of Salmonella enterica isolated from Chicken Meat and Its Products by Using Multiplex PCR
    Heba S. Amin and Abd El-Rahman A. Abd El-Rahman
    AJVS. 2015; 46(1): 155-160
    » Abstract & References » doi: 10.5455/ajvs.196302
    Cited : 5 times [Click to see citing articles]

  • Antifibrotic Effect of Curcumin on Thioacetamide Induced Liver Fibrosis
    Suzan E. Abdou, Nabil M. Taha, Abd El-Wahab A. Mandour, Mohamed A. Lebda, Hanaa R. El Hofi, Amany MSE El-Morshedy
    AJVS. 2015; 45(1): 43-50
    » Abstract & References » doi: 10.5455/ajvs.179458
    Cited : 4 times [Click to see citing articles]

  • Adverse Effects of Ivermectin in comparison with Rafoxanide on Male Rats
    Abd El-Salam F. El-Sawy, Zeynab Kh. El-Maddawy and Soaad A. Seed
    AJVS. 2015; 47(1): 119-128
    » Abstract & References » doi: 10.5455/ajvs.198997
    Cited : 4 times [Click to see citing articles]