E-ISSN 2536-9520 | ISSN 1110-2047
 

Original Article 


Comparison of Lidocaine, and Lidocaine–Neostigmine for Epidural Analgesia in Dogs

Alaa Ghazy, Ayman Atiba.

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  • Abstract
    ABSTRACT
    Objectives: Evaluate and compare the analgesic effect of epidural lidocaine and lidocaine- neostigmine combination in dogs.
    Methods: Six healthy dogs of mixed breed weighing 12–15 kg were selected for this study. All dogs received all treatments in a cross-over design with at least a one-week interval. Dogs were premeditated with Xylazine (0.5 mg/kg) and general anesthesia was induced with thiopental sodium (12.5 mg/kg) to perform the lumbosacral puncture. Epidural analgesia was done using either 6 mg/kg of lidocaine 2% or a combination of 6 mg/kg of Lidocaine 2%, with 10 µg/kg neostigmine. The degree of analgesia was evaluated using a numerical
    rating scale. Analgesia was defined as lack of response to pinprick test and pressure from hemostat clamp and was performed after one hour of epidural injection, and thereafter every 10 min until complete recovery. Heart rate (HR), respiratory rate (RR), and rectal temperature (RT) were recorded before (baseline, 0) and at every 10 min until a complete recovery was observed.
    Results: HR, RR and RT did not differ between treatments at any time point. The lidocaine–neostigmine combination produced a significant (P < 0.05) longer duration of analgesia than lidocaine alone. The addition of neostigmine resulted in a significantly longer duration of analgesia. Co-administration of epidural neostigmine and lignocaine appears to be a useful technique for postoperative analgesia as it increases the duration of analgesia
    Conclusion: Adding neostigmine to epidural administered lidocaine in dogs increases the analgesic effect on both hind limbs and perineal region.
    Short running title: Lidocaine-neostigmine epidural in the dog.

    Key words: Keywords: Analgesia, dog, epidural, lidocaine, neostigmine.


     
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    Pubmed Style

    Ghazy A, Atiba A. Comparison of Lidocaine, and Lidocaine–Neostigmine for Epidural Analgesia in Dogs. AJVS. 2020; 65(1): 90-95. doi:10.5455/ajvs.91485


    Web Style

    Ghazy A, Atiba A. Comparison of Lidocaine, and Lidocaine–Neostigmine for Epidural Analgesia in Dogs. http://www.alexjvs.com/?mno=91485 [Access: November 27, 2020]. doi:10.5455/ajvs.91485


    AMA (American Medical Association) Style

    Ghazy A, Atiba A. Comparison of Lidocaine, and Lidocaine–Neostigmine for Epidural Analgesia in Dogs. AJVS. 2020; 65(1): 90-95. doi:10.5455/ajvs.91485



    Vancouver/ICMJE Style

    Ghazy A, Atiba A. Comparison of Lidocaine, and Lidocaine–Neostigmine for Epidural Analgesia in Dogs. AJVS. (2020), [cited November 27, 2020]; 65(1): 90-95. doi:10.5455/ajvs.91485



    Harvard Style

    Ghazy, A. & Atiba, . A. (2020) Comparison of Lidocaine, and Lidocaine–Neostigmine for Epidural Analgesia in Dogs. AJVS, 65 (1), 90-95. doi:10.5455/ajvs.91485



    Turabian Style

    Ghazy, Alaa, and Ayman Atiba. 2020. Comparison of Lidocaine, and Lidocaine–Neostigmine for Epidural Analgesia in Dogs. Alexandria Journal of Veterinary Sciences, 65 (1), 90-95. doi:10.5455/ajvs.91485



    Chicago Style

    Ghazy, Alaa, and Ayman Atiba. "Comparison of Lidocaine, and Lidocaine–Neostigmine for Epidural Analgesia in Dogs." Alexandria Journal of Veterinary Sciences 65 (2020), 90-95. doi:10.5455/ajvs.91485



    MLA (The Modern Language Association) Style

    Ghazy, Alaa, and Ayman Atiba. "Comparison of Lidocaine, and Lidocaine–Neostigmine for Epidural Analgesia in Dogs." Alexandria Journal of Veterinary Sciences 65.1 (2020), 90-95. Print. doi:10.5455/ajvs.91485



    APA (American Psychological Association) Style

    Ghazy, A. & Atiba, . A. (2020) Comparison of Lidocaine, and Lidocaine–Neostigmine for Epidural Analgesia in Dogs. Alexandria Journal of Veterinary Sciences, 65 (1), 90-95. doi:10.5455/ajvs.91485





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