Abstract
This work aimed to study the effect of CIDR (Controlled Internal Drug Release) time application during breeding and non-breeding season on estradiol and progesterone profile in she camels. Nine healthy one humped she camels (Camelus Dromedaries) were randomly assigned to one of the three treatment groups during breeding and non- breeding season. All animals were synchronized with (CIDR impregnated with 1.38 progesterone was inserted vaginally. Group 1 animals (n= 3): CIDR was inserted for 7 days. Group 2 animals (n= 3): CIDR was inserted for 10 days. Group 3animals (n= 3): CIDR was inserted for 14 days. Blood samples (10ml) were withdrawn from jugular vein of each female camel into dry vacutainer tubes at days 3, 5, 7 and 7 for group (1) 3,5,7, and 9 after for group (2) and 3,5,7,9,11, and 13 for group(3). During breeding season, the overall progesterone profile (ng/ml) after CIDR application for 10 days was highest (7.68±0.77ng/ml) compared to overall progesterone profile (6.04±1.7 ng/ml and 6.99±0.45ng/ml) after CIDR application for7 and 14 days, respectively. The overall progesterone profile was fairly the same during non- breeding season. The overall estradiol profile after CIDR application for 10 days was highest (51.27±4.11pg/ml) compared to overall estradiol profile( 46.42±11.08pg/ml and 19.27±3.8pg/ml) after CIDR application for7 and 14 days, respectively during breeding season. Statistical analysis revealed significant effect (P<0.05). Similarly, during non- breeding season the overall estradiol profile after CIDR application for 10 days was highest (49.75±8.6pg/ml) compared to overall estradiol profile( 17.7±0.87pg/ml and 21.03±4.1pg/ml) after CIDR application for7 and 14 days, respectively. Statistical analysis revealed significant effect (P<0.05).In conclusion, the use of exogenous progesterone did not synchronize wave emergence in camels as follicular waves continued to emerge during the period of treatment.

Key words: CIDR, circulating estrogen and progesterone, breeding season, she-camels