E-ISSN 2536-9520 | ISSN 1110-2047
 
2025, Vol: 84
84Current Volume Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Article
Online Published: 30 Apr 2014
 


Polymorphism of Bone Morphogenetic Protein Receptor-IB (BMPR- IB) Gene with Litter Size and Kids Growth of Some Goat Breeds in Egypt

Mohamed A. Y. Helal, Hamada D.h. Mahboub, Shaaban A. Hemeda, Salah S. El Ballal, Hanim S. Heikal.


Abstract
Polymerase Chain Reaction-Restriction Fragment Length Polymorphisms (PCR–RFLP) and Single Nucleotide polymorphism (SNP) techniques were used to study the association between bone morphogenetic protein receptor IB (BMPR IB) gene polymorphism with litter size trait and kids growth. Forty four Female goats were precisely selected according to their litter size and kids growth. PCR amplification of 190 bp of the BMPR-IB gene was genotyped in all goats and sequenced only in those produced the highest and lowest litter size and kids growth. Restriction analysis of PCR-RFLP using Ava II and Hind III of the BMPR-IB gene (190-bp) do not produce restriction fragments. By DNA sequencing, eight single nucleotide polymorphisms (SNP’s) at seven different positions were obtained. Furthermore, with translation of SNPs to corresponding amino acids, change of six amino acids in three female goats were obtained as the flowing, Baladi goat with high litter size, glutamic acid (E) changed to aspartic acid (P) and isoleucine (I) changed to valine (V). In high litter size, Zaraibi goat, valine (V) changed to leucine acid (L) and glutamine (Q) changed to histidine (H). In another Zaraibi Goat with high litter size valine (V) changed to leucine acid (L) and threonine (T) changed to proline (P). These findings can be used in a marker-assisted selection (MAS) for selection for high litter size trait in goats. There are negative relationships in most goats between SNPs in BMPR IB gene and relative growth gain (RGG).

Key words: Goat, BMPR- IB gene, polymorphism


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Mohamed A. Y. Helal
Articles by Hamada D.H. Mahboub
Articles by Shaaban A. Hemeda
Articles by Salah S. El Ballal
Articles by Hanim S. Heikal
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Helal MAY, Mahboub HD, Hemeda SA, Ballal SSE, Heikal HS. Polymorphism of Bone Morphogenetic Protein Receptor-IB (BMPR- IB) Gene with Litter Size and Kids Growth of Some Goat Breeds in Egypt. AJVS. 2014; 41(1): 28-34. doi:10.5455/ajvs.155470

Web Style

Helal MAY, Mahboub HD, Hemeda SA, Ballal SSE, Heikal HS. Polymorphism of Bone Morphogenetic Protein Receptor-IB (BMPR- IB) Gene with Litter Size and Kids Growth of Some Goat Breeds in Egypt. https://www.alexjvs.com/?mno=158714 [Access: March 25, 2025]. doi:10.5455/ajvs.155470

AMA (American Medical Association) Style

Helal MAY, Mahboub HD, Hemeda SA, Ballal SSE, Heikal HS. Polymorphism of Bone Morphogenetic Protein Receptor-IB (BMPR- IB) Gene with Litter Size and Kids Growth of Some Goat Breeds in Egypt. AJVS. 2014; 41(1): 28-34. doi:10.5455/ajvs.155470


Vancouver/ICMJE Style

Helal MAY, Mahboub HD, Hemeda SA, Ballal SSE, Heikal HS. Polymorphism of Bone Morphogenetic Protein Receptor-IB (BMPR- IB) Gene with Litter Size and Kids Growth of Some Goat Breeds in Egypt. AJVS. (2014), [cited March 25, 2025]; 41(1): 28-34. doi:10.5455/ajvs.155470


Harvard Style

Helal, M. A. Y., Mahboub, . H. D., Hemeda, . S. A., Ballal, . S. S. E. & Heikal, . H. S. (2014) Polymorphism of Bone Morphogenetic Protein Receptor-IB (BMPR- IB) Gene with Litter Size and Kids Growth of Some Goat Breeds in Egypt. AJVS, 41 (1), 28-34. doi:10.5455/ajvs.155470


Turabian Style

Helal, Mohamed A. Y., Hamada D.h. Mahboub, Shaaban A. Hemeda, Salah S. El Ballal, and Hanim S. Heikal. 2014. Polymorphism of Bone Morphogenetic Protein Receptor-IB (BMPR- IB) Gene with Litter Size and Kids Growth of Some Goat Breeds in Egypt. Alexandria Journal of Veterinary Sciences, 41 (1), 28-34. doi:10.5455/ajvs.155470


Chicago Style

Helal, Mohamed A. Y., Hamada D.h. Mahboub, Shaaban A. Hemeda, Salah S. El Ballal, and Hanim S. Heikal. "Polymorphism of Bone Morphogenetic Protein Receptor-IB (BMPR- IB) Gene with Litter Size and Kids Growth of Some Goat Breeds in Egypt." Alexandria Journal of Veterinary Sciences 41 (2014), 28-34. doi:10.5455/ajvs.155470


MLA (The Modern Language Association) Style

Helal, Mohamed A. Y., Hamada D.h. Mahboub, Shaaban A. Hemeda, Salah S. El Ballal, and Hanim S. Heikal. "Polymorphism of Bone Morphogenetic Protein Receptor-IB (BMPR- IB) Gene with Litter Size and Kids Growth of Some Goat Breeds in Egypt." Alexandria Journal of Veterinary Sciences 41.1 (2014), 28-34. Print. doi:10.5455/ajvs.155470


APA (American Psychological Association) Style

Helal, M. A. Y., Mahboub, . H. D., Hemeda, . S. A., Ballal, . S. S. E. & Heikal, . H. S. (2014) Polymorphism of Bone Morphogenetic Protein Receptor-IB (BMPR- IB) Gene with Litter Size and Kids Growth of Some Goat Breeds in Egypt. Alexandria Journal of Veterinary Sciences, 41 (1), 28-34. doi:10.5455/ajvs.155470




Most Viewed Articles
Most Accessed Articles

  • Assessment of The Efficiency of Some Chemical Disinfectants Used in poultry Farms Against Coccidiosis
    Hamed Abdel tawab Samaha, Yasser Nasr Haggag, Mohammed Al sayed Nossair, Heba Mohammed Habib
    AJVS. 2013; 39(1): 82-90
    » Abstract

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract » doi: 10.5455/ajvs.154650

  • Molecular Characterization of Listeria Species Isolated from Frozen Fish
    Gaber S. Abdellrazeq, Ayman M. Kamar, Samya M. El-Houshy
    AJVS. 2014; 40(1): 1-15
    » Abstract » doi: 10.5455/ajvs.45443

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

    •
    Most Downloaded
    Top Downloaded Articles

  • Comparative Study of Cellular and Humoral Immune Response to BHV-1 Vaccines in Cattle and Buffalo Calves
    Fayrouz S. Naim; Samy A. Khalil and Helmy A. Torky
    AJVS. 2016; 51(2): 367-373
    » Abstract

  • Effect of Excess Fluoride on Reproductive Potentials in Farm Animals (Ovine)
    Ghada H. Abdel-Rahman, Hanaa A. El-Hallawany, Dohreig RA.
    AJVS. 2018; 57(2): 41-57
    » Abstract » doi: 10.5455/ajvs.296364

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Using of Polypropylene Mesh for Hernioplasty in Calves
    Mostafa M. kassam, Mahmoud H. Elkammer, Ahmed S. Korittum, Ali A. Abdel-Wahed
    AJVS. 2014; 40(1): 112-117
    » Abstract » doi: 10.5455/ajvs.47290

    •
    Most Cited Articles
    Most Cited Articles

    About Alexandria Journal of Veterinary Sciences

    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110 ... Read more.



    For best results, please use Internet Explorer or Google Chrome.

    Contact Information

    Faculty of Veterinary Medicine
    Alexandria University
    P.O.: 21944
    Abees 10th district, Alexandria
    Egypt.

    email: ajvs@alexu.edu.eg
    POLICIES & JOURNAL LINKS
    Author Login
    Reviewer Login
    About Publisher
    Advertising Policy
    Author's Rights and Obligations
    Conflict of Interest Policy
    Copyright Information
    Digital Archiving & Preservation Policies
    Editorial Policies
    Peer Review Policy
    Editorial & Peer Review Process
    License Information
    Open Access Policy
    Plagiarism Policy
    Privacy Policy
    Protection of Research Participants (Statement On Human And Animal Rights)
    Publication Ethics and Publication Malpractice Statement
    Corrections, Retractions & Expressions of Concern
    Self-Archiving Policies
    Statement of Informed Consent
    Terms of Use