E-ISSN 2536-9520 | ISSN 1110-2047
 
2024, Vol: 82
82Current Volume Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Article 


Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model

Salma Gomaa, Hoda Elkhenany, Howaida Abu-Ahmed, Hosam Gafaar, Ramadan Abdelwahed.


Abstract
In this study, gelatin (GE) will be used as a carrier to enhance platelet-rich plasma's (PRP) effects on the wound-healing process. PRP/GE was created by conjugating 20% GE with freshly prepared autologous PRP. Following rabbits with experimentally generated full-thickness skin wounds, the ability of the skin to regenerate was evaluated. Evaluation considered the macroscopic features of wounds, wound healing rate % and histologic findings for specimens collected after 3, 10 and 21 days. The PRP/GE treated wounds revealed noticeably improved and better closure. This improvement may be attributable to the advantages of combining PRP with GE as a bioactive substance that may regulate the release of growth factors and support angiogenesis. It might be concluded that PRP/GE has the ability to quicken the healing process. The therapeutic impact of PRP was boosted by the GE carrier. According to these data, PRP/GE may be suggested as a viable therapy for wound healing.

Key words: PRP, gelatin, wound healing, full-thickness wounds, bioactive material, skin regeneration, growth factors


 
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How to Cite this Article
Pubmed Style

Gomaa S, Elkhenany H, Abu-Ahmed H, Gafaar H, Abdelwahed R. Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. AJVS. 2024; 80(1): 164-171. doi:10.5455/ajvs.182328

Web Style

Gomaa S, Elkhenany H, Abu-Ahmed H, Gafaar H, Abdelwahed R. Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. https://www.alexjvs.com/?mno=182328 [Access: September 13, 2024]. doi:10.5455/ajvs.182328

AMA (American Medical Association) Style

Gomaa S, Elkhenany H, Abu-Ahmed H, Gafaar H, Abdelwahed R. Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. AJVS. 2024; 80(1): 164-171. doi:10.5455/ajvs.182328


Vancouver/ICMJE Style

Gomaa S, Elkhenany H, Abu-Ahmed H, Gafaar H, Abdelwahed R. Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. AJVS. (2024), [cited September 13, 2024]; 80(1): 164-171. doi:10.5455/ajvs.182328


Harvard Style

Gomaa, S., Elkhenany, . H., Abu-Ahmed, . H., Gafaar, . H. & Abdelwahed, . R. (2024) Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. AJVS, 80 (1), 164-171. doi:10.5455/ajvs.182328


Turabian Style

Gomaa, Salma, Hoda Elkhenany, Howaida Abu-Ahmed, Hosam Gafaar, and Ramadan Abdelwahed. 2024. Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. Alexandria Journal of Veterinary Sciences, 80 (1), 164-171. doi:10.5455/ajvs.182328


Chicago Style

Gomaa, Salma, Hoda Elkhenany, Howaida Abu-Ahmed, Hosam Gafaar, and Ramadan Abdelwahed. "Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model." Alexandria Journal of Veterinary Sciences 80 (2024), 164-171. doi:10.5455/ajvs.182328


MLA (The Modern Language Association) Style

Gomaa, Salma, Hoda Elkhenany, Howaida Abu-Ahmed, Hosam Gafaar, and Ramadan Abdelwahed. "Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model." Alexandria Journal of Veterinary Sciences 80.1 (2024), 164-171. Print. doi:10.5455/ajvs.182328


APA (American Psychological Association) Style

Gomaa, S., Elkhenany, . H., Abu-Ahmed, . H., Gafaar, . H. & Abdelwahed, . R. (2024) Evaluation of Gelatin Loaded PRP for Full-thickness Wound Healing in Rabbit Model. Alexandria Journal of Veterinary Sciences, 80 (1), 164-171. doi:10.5455/ajvs.182328




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    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110 ... Read more.



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