E-ISSN 2536-9520 | ISSN 1110-2047
 
2025, Vol: 85
85Current Volume Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Article 


The Histological and Biochemical Effects of Saffron on Schistosoma mansoni Infected Mice

Osama M. Badr, Walead A. Mohamed, Mohamed E. Alkafafy, Omaima A. Khamiss.


Abstract
The present study was designed to evaluate the antischistosomal activity of the herbal medicine; saffron on mice infected with Schistosoma mansoni species. Mice were divided into three groups; each group contains seven mice. The first group was served as normal control and mice of the other two groups was individually infected with 60±5 Schistosoma mansoni cercaria. One of them was the infected group and the other group mice were orally treated with 0.2 ml of saffron extract (100mg/kg) six weeks post infection three times weekly for four weeks. After the last dose; all mice were sacrificed. Mice liver infected with Schistosoma mansoni cercaria displayed an extremely elevation (P ≤ 0.001) in liver weight, ova count, ALT and AST levels. Otherwise, it induced an extremely reduction (P ≤ 0.001) in both albumin and total protein levels. Saffron extract modulated all the previous mentioned parameters to be near to normal values. Histologically, mice liver infected with Schistosoma mansoni cercaria showed portal fibrosis, granulomatous nodules, and focal cell infiltration. Saffron extract ameliorated the histological structure of liver by reducing the different histopathological effects induced with Schistosoma mansoni cercaria. Finally, saffron has a powerful antischistosomal activity in mice infected with Schistosoma mansoni cercaria.

Key words: Schistosoma mansoni, liver weight, ova count, ALT, AST, albumin, total proteins, saffron.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Osama M. Badr
Articles by Walead A. Mohamed
Articles by Mohamed E. Alkafafy
Articles by Omaima A. Khamiss
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Badr OM, Mohamed WA, Alkafafy ME, Khamiss OA. The Histological and Biochemical Effects of Saffron on Schistosoma mansoni Infected Mice. AJVS. 2017; 53(1): 100-107. doi:10.5455/ajvs.257434

Web Style

Badr OM, Mohamed WA, Alkafafy ME, Khamiss OA. The Histological and Biochemical Effects of Saffron on Schistosoma mansoni Infected Mice. https://www.alexjvs.com/?mno=257434 [Access: March 25, 2025]. doi:10.5455/ajvs.257434

AMA (American Medical Association) Style

Badr OM, Mohamed WA, Alkafafy ME, Khamiss OA. The Histological and Biochemical Effects of Saffron on Schistosoma mansoni Infected Mice. AJVS. 2017; 53(1): 100-107. doi:10.5455/ajvs.257434


Vancouver/ICMJE Style

Badr OM, Mohamed WA, Alkafafy ME, Khamiss OA. The Histological and Biochemical Effects of Saffron on Schistosoma mansoni Infected Mice. AJVS. (2017), [cited March 25, 2025]; 53(1): 100-107. doi:10.5455/ajvs.257434


Harvard Style

Badr, O. M., Mohamed, . W. A., Alkafafy, . M. E. & Khamiss, . O. A. (2017) The Histological and Biochemical Effects of Saffron on Schistosoma mansoni Infected Mice. AJVS, 53 (1), 100-107. doi:10.5455/ajvs.257434


Turabian Style

Badr, Osama M., Walead A. Mohamed, Mohamed E. Alkafafy, and Omaima A. Khamiss. 2017. The Histological and Biochemical Effects of Saffron on Schistosoma mansoni Infected Mice. Alexandria Journal of Veterinary Sciences, 53 (1), 100-107. doi:10.5455/ajvs.257434


Chicago Style

Badr, Osama M., Walead A. Mohamed, Mohamed E. Alkafafy, and Omaima A. Khamiss. "The Histological and Biochemical Effects of Saffron on Schistosoma mansoni Infected Mice." Alexandria Journal of Veterinary Sciences 53 (2017), 100-107. doi:10.5455/ajvs.257434


MLA (The Modern Language Association) Style

Badr, Osama M., Walead A. Mohamed, Mohamed E. Alkafafy, and Omaima A. Khamiss. "The Histological and Biochemical Effects of Saffron on Schistosoma mansoni Infected Mice." Alexandria Journal of Veterinary Sciences 53.1 (2017), 100-107. Print. doi:10.5455/ajvs.257434


APA (American Psychological Association) Style

Badr, O. M., Mohamed, . W. A., Alkafafy, . M. E. & Khamiss, . O. A. (2017) The Histological and Biochemical Effects of Saffron on Schistosoma mansoni Infected Mice. Alexandria Journal of Veterinary Sciences, 53 (1), 100-107. doi:10.5455/ajvs.257434




Most Viewed Articles
Most Accessed Articles

  • Assessment of The Efficiency of Some Chemical Disinfectants Used in poultry Farms Against Coccidiosis
    Hamed Abdel tawab Samaha, Yasser Nasr Haggag, Mohammed Al sayed Nossair, Heba Mohammed Habib
    AJVS. 2013; 39(1): 82-90
    » Abstract

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Influence of Combined Administration of Turmeric and Black seed on Selected Biochemical Parameters of Diabetic Rats
    Sabry M. El-Bahr, Nabil M. Taha, Mahdy A. Korshom, Abd EL-Wahab A. Mandour, Mohamed A. Lebda
    AJVS. 2014; 41(1): 19-27
    » Abstract » doi: 10.5455/ajvs.154650

  • Molecular Characterization of Listeria Species Isolated from Frozen Fish
    Gaber S. Abdellrazeq, Ayman M. Kamar, Samya M. El-Houshy
    AJVS. 2014; 40(1): 1-15
    » Abstract » doi: 10.5455/ajvs.45443

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

    •
    Most Downloaded
    Top Downloaded Articles

  • Comparative Study of Cellular and Humoral Immune Response to BHV-1 Vaccines in Cattle and Buffalo Calves
    Fayrouz S. Naim; Samy A. Khalil and Helmy A. Torky
    AJVS. 2016; 51(2): 367-373
    » Abstract

  • Effect of Excess Fluoride on Reproductive Potentials in Farm Animals (Ovine)
    Ghada H. Abdel-Rahman, Hanaa A. El-Hallawany, Dohreig RA.
    AJVS. 2018; 57(2): 41-57
    » Abstract » doi: 10.5455/ajvs.296364

  • Growth Performance, Blood Parameters, Immune response and Carcass Traits of Broiler Chicks Fed on Graded Levels of Wheat Instead of Corn without or With Enzyme Supplementation
    Mohamed I. El-Katcha, Mosaad A. Soltan, Hany F. El-Kanwy, EL-syaed R. kawarie
    AJVS. 2014; 40(1): 95-111
    » Abstract » doi: 10.5455/ajvs.48232

  • Physiological and Oxidative Stress Biomarkers in the Freshwater Nile Tilapia, Oreochromis niloticus L., exposed to sublethal doses of cadmium
    Ahmed M. EL-Gazzar, Khalid E. Ashry, Yasser S. El-Sayed
    AJVS. 2014; 40(1): 29-43
    » Abstract » doi: 10.5455/ajvs.48333

  • Using of Polypropylene Mesh for Hernioplasty in Calves
    Mostafa M. kassam, Mahmoud H. Elkammer, Ahmed S. Korittum, Ali A. Abdel-Wahed
    AJVS. 2014; 40(1): 112-117
    » Abstract » doi: 10.5455/ajvs.47290

    •
    Most Cited Articles
    Most Cited Articles

    About Alexandria Journal of Veterinary Sciences

    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110 ... Read more.



    For best results, please use Internet Explorer or Google Chrome.

    Contact Information

    Faculty of Veterinary Medicine
    Alexandria University
    P.O.: 21944
    Abees 10th district, Alexandria
    Egypt.

    email: ajvs@alexu.edu.eg
    POLICIES & JOURNAL LINKS
    Author Login
    Reviewer Login
    About Publisher
    Advertising Policy
    Author's Rights and Obligations
    Conflict of Interest Policy
    Copyright Information
    Digital Archiving & Preservation Policies
    Editorial Policies
    Peer Review Policy
    Editorial & Peer Review Process
    License Information
    Open Access Policy
    Plagiarism Policy
    Privacy Policy
    Protection of Research Participants (Statement On Human And Animal Rights)
    Publication Ethics and Publication Malpractice Statement
    Corrections, Retractions & Expressions of Concern
    Self-Archiving Policies
    Statement of Informed Consent
    Terms of Use