E-ISSN 2536-9520 | ISSN 1110-2047
 
2026, Vol: 88
88Current Volume Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Article
Online Published: 27 Nov 2025
 


Investigation of the Antiviral Activity of Zinc Oxide Nano Particles Against Foot and Mouth Virus to Be Used in Emergency Cases

Azza M. Mohamed, Atwa M. Hassan, Mohamed A. Gamil, Lubna F. Farahat.


Abstract
The nanotechnology has enabled to use very small particles of the zinc nanoparticles against most of the microbial and viral disease. The use of metal nanoparticles provides opportunity for novel antiviral therapies.
Metal may attack many targets in the viruses especially those of resistant strain. Zinc oxide nanoparticles give anti-viral activity at the early stage of viral replication as virucidal agent or an inhibitor of viral entry binding, fusion, and infectivity and inhibit post-entry stages of the virus life cycle. All these properties make the zinc oxide abroad spectrum agent. In this study the antiviral activity of different concentration of zinc oxide nanoparticles (ZnO Np) 5-50 μm particles size, measured with electron microscope, against FMD virus on baby hamster kidney cell line where we found that concentration of 400 μm of ZnO NP has no cytotoxic effect on cell culture inducing 100% reduction in the virus titer. This finding could be in consideration as a preliminary study to further in vivo application on experimentally infected animals with FMD virus aiming to minimize the economic losses and aiding to control the disease spread.

Key words: FMD, ZnO, Nanoparticles., antiviral .


 
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How to Cite this Article
Pubmed Style

Mohamed AM, Hassan AM, Gamil MA, Farahat LF. Investigation of the Antiviral Activity of Zinc Oxide Nano Particles Against Foot and Mouth Virus to Be Used in Emergency Cases. AJVS. 2026; 88(0): 244-250. doi:10.5455/ajvs.268067

Web Style

Mohamed AM, Hassan AM, Gamil MA, Farahat LF. Investigation of the Antiviral Activity of Zinc Oxide Nano Particles Against Foot and Mouth Virus to Be Used in Emergency Cases. https://www.alexjvs.com/?mno=268067 [Access: February 04, 2026]. doi:10.5455/ajvs.268067

AMA (American Medical Association) Style

Mohamed AM, Hassan AM, Gamil MA, Farahat LF. Investigation of the Antiviral Activity of Zinc Oxide Nano Particles Against Foot and Mouth Virus to Be Used in Emergency Cases. AJVS. 2026; 88(0): 244-250. doi:10.5455/ajvs.268067


Vancouver/ICMJE Style

Mohamed AM, Hassan AM, Gamil MA, Farahat LF. Investigation of the Antiviral Activity of Zinc Oxide Nano Particles Against Foot and Mouth Virus to Be Used in Emergency Cases. AJVS. (2026), [cited February 04, 2026]; 88(0): 244-250. doi:10.5455/ajvs.268067


Harvard Style

Mohamed, A. M., Hassan, . A. M., Gamil, . M. A. & Farahat, . L. F. (2026) Investigation of the Antiviral Activity of Zinc Oxide Nano Particles Against Foot and Mouth Virus to Be Used in Emergency Cases. AJVS, 88 (0), 244-250. doi:10.5455/ajvs.268067


Turabian Style

Mohamed, Azza M., Atwa M. Hassan, Mohamed A. Gamil, and Lubna F. Farahat. 2026. Investigation of the Antiviral Activity of Zinc Oxide Nano Particles Against Foot and Mouth Virus to Be Used in Emergency Cases. Alexandria Journal of Veterinary Sciences, 88 (0), 244-250. doi:10.5455/ajvs.268067


Chicago Style

Mohamed, Azza M., Atwa M. Hassan, Mohamed A. Gamil, and Lubna F. Farahat. "Investigation of the Antiviral Activity of Zinc Oxide Nano Particles Against Foot and Mouth Virus to Be Used in Emergency Cases." Alexandria Journal of Veterinary Sciences 88 (2026), 244-250. doi:10.5455/ajvs.268067


MLA (The Modern Language Association) Style

Mohamed, Azza M., Atwa M. Hassan, Mohamed A. Gamil, and Lubna F. Farahat. "Investigation of the Antiviral Activity of Zinc Oxide Nano Particles Against Foot and Mouth Virus to Be Used in Emergency Cases." Alexandria Journal of Veterinary Sciences 88.0 (2026), 244-250. Print. doi:10.5455/ajvs.268067


APA (American Psychological Association) Style

Mohamed, A. M., Hassan, . A. M., Gamil, . M. A. & Farahat, . L. F. (2026) Investigation of the Antiviral Activity of Zinc Oxide Nano Particles Against Foot and Mouth Virus to Be Used in Emergency Cases. Alexandria Journal of Veterinary Sciences, 88 (0), 244-250. doi:10.5455/ajvs.268067




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    About Alexandria Journal of Veterinary Sciences

    The Alexandria Journal of Veterinary Sciences (AJVS) Official Journal of Faculty of Veterinary Medicine, Alexandria University   ISSN: 1110-204 ... Read more.



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    Faculty of Veterinary Medicine
    Alexandria University
    P.O.: 21944
    Abees 10th district, Alexandria
    Egypt.

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